Home › Botanicals & Balance

Vitamin K and Calcium: How Vitamins K1 and K2 Work With Vitamin D

The vitamin that tells calcium where to go.

Quick answer

Vitamin K is a group of fat-soluble vitamins, mainly K1 (phylloquinone) from leafy green vegetables and K2 (menaquinones) from fermented foods and some animal products. Vitamin K activates proteins that need it to work, including clotting factors, osteocalcin, which helps bind calcium into bone, and matrix Gla protein, which helps keep calcium out of soft tissues such as blood vessels. Vitamin D increases calcium absorption, while vitamin K helps direct where that calcium goes, which is why the two are often paired. Adequate intake is about 90 mcg a day for women and 120 mcg for men. Vitamin K can reduce the effect of warfarin, so people taking it must keep their intake consistent and talk to their doctor before using supplements.

Key takeaways

Vitamin D gets the spotlight for calcium, but vitamin K quietly decides where that calcium ends up.

Vitamin K1 vs K2

Vitamin K1Vitamin K2
NamePhylloquinoneMenaquinones (MK-4, MK-7)
Main sourcesKale, spinach, broccoliNatto, cheese, egg yolks
Main roleBlood clottingCalcium in bones and vessels

How vitamin K manages calcium

Osteocalcin

Activated by vitamin K, it helps bind calcium into bone.

Matrix Gla protein

Helps keep calcium from building up in soft tissues.

The vitamin D partnership

Vitamin D brings calcium in; vitamin K helps put it in the right place.

Getting enough

VertiFree includes vitamin K with vitamin D to support healthy calcium regulation, alongside ligustrum, Sophora japonica and 15 herbs.

Important: vitamin K can reduce the effect of warfarin (Coumadin). If you take warfarin or another blood thinner, do not start any vitamin K supplement, including VertiFree, without your doctor's approval.

Sources

  1. NIH Office of Dietary Supplements – "Vitamin K" fact sheet.
  2. Beulens J.W. et al. – "The role of menaquinones (vitamin K2) in human health," British Journal of Nutrition, 2013.
  3. Linus Pauling Institute, Oregon State University – "Vitamin K."

Common questions

What does vitamin K do for calcium?

It activates proteins that bind calcium into bone and keep it out of soft tissues.

What is the difference between K1 and K2?

K1 comes from leafy greens; K2 comes from fermented and animal foods.

Can I take vitamin K with warfarin?

Only with your doctor's approval, as it can reduce warfarin's effect.

← Back to home

↑